Environmental and genetic factors in pediatric inflammatory demyelinating diseases
نویسندگان
چکیده
منابع مشابه
Kidney Diseases: Environmental and Genetic Factors
The spectrum of hereditary (autosomal dominant) renal cancer syndrome is widening with time. Von Hippel-Lindau (VHL) disease was first to be identified. Attention has been focused on novel localizations of VHL disease (in addition to central nervous system and retinal involvement, bilateral and multifocal renal cell carcinoma [RCC], and pheochromocytoma), such as pancreas cysts and tumors and, ...
متن کاملEditorial: Microbial and Environmental Factors in Autoimmune and Inflammatory Diseases
Pathogenesis of many autoinflammatory and autoimmune diseases is largely driven by inappropriate or inadequate immune responses toward environmental challenges. Most of them are multifactorial. For example, assessment of disease risk factors in rheumatoid arthritis (RA) brings the share of genetic predisposition to 50–60%, with the rest attributed to environmental factors (1). Thus, the disease...
متن کاملPediatric demyelinating diseases: multiple sclerosis or not?
tral nervous system demyelination have been increasingly recognized in children. Moreover, a much higher proportion of children (as compared to adults) suffer from a monophasic (and not chronic) demyelinating event such as acute disseminated encephalomyelitis or isolated optic neuritis, and transverse myelitis, often post-infectious. Differentiation between such acute monophasic illnesses and a...
متن کاملDifferential diagnosis and evaluation in pediatric inflammatory demyelinating disorders.
Major advances have been made in the clinical and radiologic characterization of children presenting with the different forms of an acquired inflammatory demyelinating syndrome (ADS) such as acute disseminating encephalomyelitis, neuromyelitis optica spectrum disorders, and clinically isolated syndromes. Nevertheless, a proportion of cases that present with similar symptoms are due to a broad s...
متن کاملInflammatory Demyelinating Diseases of Childhood: Case Report and Literature Review.
Multiple sclerosis (MS) and acute disseminated encephalomyelitis (ADEM) are demyelinating inflammatory diseases, considered to have a striking pathophysiological resemblance. However, due to the differences in both clinical course and clinical approaches, it is important to differentiate between the two conditions, to plan further investigations and therapy protocols. These diseases have simila...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Neurology
سال: 2016
ISSN: 0028-3878,1526-632X
DOI: 10.1212/wnl.0000000000003029